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The peptide as well as its Cu (II) chelate have anti-inflammatory and tissue remodeling properties

These polymorphisms are common in the population and can influence homocysteine levels and methylation efficiency

However, their therapeutic potential could be limited as a protracted use will lead to tolerance to analgesic effects requiring escalating doses that is associated with side effects such as respiratory depression

Patients typically receive injections once or twice weekly for the first two weeks, followed by monthly maintenance doses, making the treatment cost-effective for those requiring consistent B12 supplementation