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In the presence of the appropriate ligands (bile acids, T3, retinoids, etc.), the two HREs in the apoC-II proximal promoter interact with the HCR.1 enhancer to promote liver-specific expression of the APOC2 gene
Owing to its rare occurrence, even the most renowned clinical cancer centers do not have a large enough cohort of oral melanoma cases to reliably and significantly correlate the histologic findings with prognosis
R., Brenton A
Nano-Micro Lett 13:182
