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This is well within community practice and trades a slower start for a smoother body adjustment

While Id posted a link above to phase 3 clinical trial results showing .8% of folks experienced the delayed reaction it sure seems to be more widespread than that

Foot Ankle Clin 12:553567 Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JH (2017) Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation

Remarkably, the same narrow dose range proves effective whether counteracting dopamine depletion, serotonin syndrome, glutamate excitotoxicity, or GABA tolerance