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Moreover, Nrf2 knockout mice were more sensitive to chronic stress than their wild-type counterparts, highlighting the critical role of the Nrf2 cytoprotective response in mitigating depression [146]

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Acknowledgments The authors would like to thank the institutional support of the Centro de Cincias da Sade, Ps-Graduao em Produtos Naturais e Sintticos Bioativos, and Universidade Federal da Paraba

A.KhoshnoodiJ.Jeddi-TehraniM.ZarnaniA
