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Growth hormone stimulates hepatic IGF-1 production by binding to growth hormone receptors on liver cells, triggering intracellular signaling through the JAK2/STAT5 pathway that upregulates IGF-1 gene expression

If a patient without a diagnosed vitamin B12 deficiency is receiving the vitamin through regular injections to experience the multitude of benefits, the frequency of these injections can vary quite a bit depending on the reason they are getting the injections (weight loss treatments will likely have a higher frequency of vitamin injections than other treatments) and this timeline will be established by the patient and the specialist providing the injections to ensure that the treatment is both as safe and as effective as possible

Kridel, S