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Moreover, GPX4 levels were elevated on treatment with SCLA2 and derived alkyne probes SCLA2a and SCLA2b (Extended Data Fig

In in vitro experiments, NRF2 expression was reduced in IL-22-stimulated HaCaT cells, while the addition of SFN partially restored NRF2 expression

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GHK-Cu is a naturally occurring tripeptide complex glycyl-L-histidyl-L-lysine that binds copper(II) ions with high affinity