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Upon cell incubation, the cell extracts are analyzed by MS techniques and metabolomic data is retrieved, metabolites annotated and metabolomic patterns associated to each specific mechanism of drug-induced toxicity are identified
doi: 10.1016/j.jclepro.2016.02.034

The process of protein oxidation begins when ROS interact with specific amino acids, such as cysteine, methionine, and tyrosine, which contain sulfur or aromatic groups that are highly susceptible to oxidation

Tumor necrosis factor blocking therapy alters joint inflammation and hypoxia
