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This review covers potential paths for SARS-CoV-2 infection of the brain
"In REDEFINE 1, CagriSema provided weight loss in the highest range of efficacy observed with existing weight loss interventions.Investigators were allowed some flexibility in dose adjustments to balance efficacy and safety, but regardless of dose adjustments participants lost significant weight

It is possible that there is a bidirectional link between the two rather than a causal one-way relationship

Free Radic Biol Med 21: 335348
