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The histone methyltransferase EZH2 and its repressive mark H3K27Me3 are upregulated in endometrial stromal cells (ESCs) of endometriosis patients, contributing to defective decidualization
These effects include the destruction of hepatic sinus endothelium, CYP450 enzyme system disorder and transporter-mediated cholestasis
It was shown that polymorphisms in the genes encoding glutathione S-transferases are associated with the development of these diseases
