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This later method should be more sensitive than DCE-MRI because water is smaller than gadolinium-based contrast agent (18 Da versus 550 Da) but interpretation of the output measure can be more complex because it reflects the combination of 2 different transports of water from the blood to the brain extravascular and extracellular spaces (518, 519)

10.1097/tp.0000000000001484 203 NuckleyD

The gene expression changes trend toward a younger, healthier pattern, which is the foundation for its anti-aging applications
