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Gut-Derived Exosomes Mediate Memory Impairment After Intestinal Ischemia/Reperfusion via Activating Microglia

The safety of these nanomedicines in humans needs rigorous evaluation
Ellagic acid (EA), a natural antioxidant, mitigates aging-related oxidative damage in the kidney by upregulating the mRNA and protein expression of SIRT1 and NRF2, while also promoting the deacetylation of NRF2 protein [70]

On the other hand, it is worthy to note that although ALA treatment could effectively increase the Nrf2-mediated anti-oxidative enzymes activities, the increment level was not uniformly detected across all enzymes
