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Knock-out of the Igf2r / M6pr resulted in increased serum and tissue levels of IGF-II and fetal overgrowth (140% of wild-type birth weight) (22)

We have shown that overexpression of desnutrin/ATGL in COS-7 cells increased FFA release to the medium, decreasing intracellular stores of TAG without affecting intracellular phospholipid stores (130)

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