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10.1007/s12291-014-0446-0 121 PonistS.ZlohM.BauerovaK
Sirtuin deacetylases, also known as class III KDACs, are localized in various cellular compartments, including the nucleus (SIRT1 and SIRT6), nucleolus (SIRT7), cytoplasm (SIRT2), and mitochondria (SIRT3, SIRT4, and SIRT5) [61]
Furthermore, some cancer cells can develop resistance to oxidative stress, making antioxidant therapy less effective
