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10.1007/s00394-014-0651-x PMID: 24442425 [DOI] [PubMed] [Google Scholar] [46].Amadieu C, Leclercq S, Coste V, et al

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A more in-depth analysis of the effect of oxygen levels permitted conditions to be optimized [63, 64] and showed that -butyrobetaine production was dramatically decreased when the biotransformation was performed under aerobic conditions as a consequence of the inhibition of crotonobetaine reductase by oxygen [14, 16, 63, 65]

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