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Another study comparing groups of severely obese versus non-obese patients showed that 34.1% of people in the obesity group had vitamin B12 deficiency, compared with 12.5% in the control (non-obese) group

Concurrent medical conditionssuch as Crohn's disease, coeliac disease, or gastric surgerycan impair absorption and delay treatment effects

Clinical Research Findings In a comprehensive safety analysis published in 2013, researchers evaluated data from six randomized controlled trials spanning five years and involving approximately 900 adult participants

Its ability to interact with lipolytic pathways without the confounding growth-promoting effects of full GH makes it particularly useful for dissecting the metabolic arm of GH signalling in laboratory models