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Administration of this peptide has been associated with the release of serotonin in specific brain regions, notably the nigrostriatal areas, and has beneficial effects on dopaminergic systems

Cochrane review (2007): A review of 13 studies in more than 900 patients with hepatitis B and C found that silymarin alone or in combination with other interventions did not reduce complications from liver disease, reduce mortality, or improve liver microscopic appearance relative to placebo
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