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Dermoscopy reveals pseudo-network patterns, angulated lines, and follicular pigmentation

databases from inception through August 2023 was conducted using the search Mesh terms Carnitine or Acetylcarnitine AND the broad search Mesh terms Psychiatry, Mental Disorders, Neurology, Nervous System Diseases, Neurocognitive Disorders, Neurodegenerative disease, Schizophrenia OR specific psychiatric and neurological disorders Alzheimer Disease, Parkinson Disease, Stroke, Depressive Disorder, Anxiety Disorders, Mania, Multiple Sclerosis, Huntington Disease, Down Syndrome, Autistic Disorder, Brain Injuries, Traumatic, Epilepsy, Obsessive-Compulsive Disorder, Attention Deficit Disorder with Hyperactivity, Bipolar Disorder or Amyotrophic Lateral Sclerosis

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The C/EBP expression in microglia has indeed been observed to increase in spinal cord of ALS animal models and human ALS patients (97).TDP-43 interacts with NF-B, a key factor contributing to the inflammatory response, and activates NF-B in microglia (98)