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Highlights: Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation Fix protein interactions to allow identification of weak or transient protein interactions Protein crosslinking to create bioconjugates via single-step reactions Crosslink oriented antibodies to Protein A or G agarose Immobilize proteins onto amine-coated surfaces Specifications Specifications Frequently Asked Questions (FAQs) Will the DSS crosslinked product become unlinked as a result of boiling, incubation with SDS, high salt, high or low pH or any other means

Br J Pharmacol 2009

Vander Heiden MG, Cantley LC, Thompson CB