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IR is considered an underlying factor in PCOS, playing a crucial role in its pathogenesis

Liang, X., Ji, S., Chen, Y

& Maneiro, E

Several human and animal studies reported that the proinflammatory cytokines IFN-, TNF-, IL-1, IL-6, and IL-8 are inhibited, whereas IL-10 and TGF- are upregulated in response to butyrate (25)
