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Also, by inhibiting microglial activation through CB2 receptor inhibition, it can reduce neuronal inflammation through downregulation of NF-B (47)

A., Holmes, W

L-cysteine and NAC are generally well-tolerated, but possible side effects include: Nausea Vomiting Diarrhea Headache Abdominal pain Allergic reactions (rare) High doses may impact blood pressure or kidney function in sensitive individuals, so medical supervision is advised for long-term or high-dose use

For instance, 13-HODE may increase reverse cholesterol transport early in atherosclerosis through PPAR activation
