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Sadick, J

Therefore, it is not surprising that depletion of either T(SH) 2 [182] or tryparedoxin [183] causes severe growth defects and increases the parasites sensitivity towards oxidative agents

However, GPX3 also serves to protect tumor cells from exogenous oxidant damage by enhancing the removal of hydrogen and soluble lipid hydroperoxides from the extracellular tumor environment (52)

Peroxiredoxins The universal family of cysteine-dependent peroxidase enzymes known as peroxiredoxins (Prxs) is primarily responsible for controlling the amounts of peroxide in cells
