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Myeloid differentiation protein2 has been identified to activate TLRs, and participation in TLR4-NOX4 complex formation may contribute to oxidative and inflammatory damage [316]

doi: 10.1002/phar.2489
Glutathiones ability to neutralise these ROS has led to it often being referred to as the master antioxidant

10.3389/fphar.2021.824885 22 Cougnard-GregoireA.MerleB.AslamT.SeddonJ
