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SubQ delivery is frequently used in clinical practice because it is less invasive and often better tolerated than intramuscular administration
The finding that partial IGFBP-3 proteolysis, such as in pregnancy, does not disrupt the ternary complex, has questioned its significance

Medications like Liraglutide and Semaglutide are thought to support kidney health through these improvements [3]

These are seen in several other types of EDS as well, typically in classical EDS
