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Description
Curcumin directly binds to small A peptides to block the aggregation and fibril formation, which attenuates their destructive effect on cell membranes, thereby reducing cytotoxicity and improving cell survival (Zhang et al., 2010)

133 Similarly, mice lacking ZIP3 exhibit decreased CD4 + CD8 + double-positive (DP) thymocytes but increased CD4 + and CD8 + single-positive thymocytes, indicating its role in regulating T cell development
doi: 10.1113/jphysiol.2004.068320