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Over the life of a vial, this adds up

It further maintains central nervous system homeostasis by normalizing disrupted neurotransmitter signaling involving dopamine, serotonin, and gamma-aminobutyric acid (GABA), essential for stabilizing synaptic function and ensuring neuromuscular coordination after injury or toxin exposure [43, 45]
Abbreviations ATS/IDSA: American Thoracic Society/Infectious Diseases Society of America M

This is particularly relevant given that (i) the availability of cobalt as a trace element varies significantly on both land and in water [[23], [24], [25]], and (ii) that the corrin ring is so difficult to make [[26], [27], [28]]