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2010), demonstrating that astrocytes continuously consume GSH and that this consumption has to be matched by appropriate synthesis of GSH to maintain a constant GSH concentration in the cells

These pathological interwoven processes activate multimodal cell death pathways, such as apoptosis, necrosis, autophagy, and ferroptosis, posing a major challenge to neuroprotective treatment strategies

Certain vitamins and supplements compete for absorption, reducing effectiveness

doi: 10.1016/j.vph.2021.106946 19 ScozziDCanoMMaLZhouDZhuJHOHalloranJAet al
