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Description
Naltrexone is an antagonist for opiate/endorphin receptors, it is mostly used for patients fighting narcotic and alcohol dependence
This age-related NAD+ depletion impairs mitochondrial energy production, reduces SIRT1 activity, compromises DNA repair mechanisms, and accelerates cellular senescence
Transcription factors and cis -acting elements important for mouse and rat GCLM genes are similar to the human gene
With a false positive rate (FPR) of 5%, this algorithm has a detection rate of 93% for EoPE and 61% for LoPE [76]
