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3 Reactive oxygen species (ROS)-mediated inhibition of glycolysis reroutes flux into the oxidative arm of the pentose phosphate pathway
TF neutralizes iron-induced toxicity in iRPE cells Because lipid peroxidation leads to iron overload in iRPE cells, we further investigated the mechanisms of action of TF on iRPE cells exposed to FeCl 3 associated with nitrilotriacetate, which forms a stable iron complex in solution
