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The systematic review of the literature we conducted to find evidence of the beneficial effects of substances advertised as brain doping on physical performance or the improvement of athletic performance did not yield satisfactory findings that could significantly resolve our doubts regarding the status of the considered compounds

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Characterization of the intestine-specific TRX-3 have shown that the trx-3 ( tm2820 ) mutant has no significant difference in reproductive capacity, longevity, and resistance to stress (including heat-treatment, juglone and paraquat exposure) compared to the wild-type, though they exhibit a decrease in physical size and a shorter timing of their defecation cycle [154]