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Description
213 BM-MSC-EVs can effectively modify macrophage responses, even with inflammatory triggers such as hypo- and hyperinflammatory ARDS plasma
Reductive stress refers to an increase in NADPH and GSH and may result in adverse cellular events such as protein misfolding and aggregation, mitochondrial dysfunction, pathological gene expression, and increased susceptibility to apoptosis (11, 14, 60, 98, 106, 112, 114)
Notably, in addition to trying to block potential downstream detrimental effects, new therapies need to be designed that preserve and boost astrocytic defences and improve astrocytic homoeostasis
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