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Relapse of pathological angiogenesis In many cancers, anti-VEGF treatment must be given continuously, but this leads to toxicity, worsening the quality of life and/or exacerbating drug resistance mediated by treatment-induced epigenetic changes

2006;291:E683E690

doi: 10.1039/d2fo02369e 58 ChoiG.BessmanN

Liver biopsy and quantitative analysis of hepatic copper concentrations is required for definitive diagnosis and staging of the disease
