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Description
Muller TD, Clemmensen C, Finan B, DiMarchi RD, Tschop MH

Its mechanism exemplifies how some peptides may be viable orally when their activity does not require systemic absorption

Bioeng Transl Med

In this Review, we focus on advances in our understanding of inhibition of the HGF/c-MET pathway in patients with gastro-intestinal cancers, the prominent challenges facing the clinical translation and implementation of agents targeting HGF/c-MET, and discuss the various efforts, and associated obstacles to the discovery and validation of biomarkers that will enable patient stratification in this context
