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Data availability Atomic coordinates and structure factors for the crystal structures of the GAS7 F-BAR domain and GAS7cb have been deposited in the Protein Data Bank, under the accession codes 6IKN and 6IKO, respectively

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For a toxicology reading, rapid clearance and metabolism to endogenous building blocks cut in a reassuring direction: there is little basis for the peptide itself to bioaccumulate to toxic steady-state concentrations, and its degradation products are not exotic xenobiotics