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Insomnia or Sleep Disturbances : It might influence sleep patterns, leading to difficulty falling asleep or staying asleep
Overexpression of wild-type STUB1 , but not of a catalytically inactive mutant, leads to reduced BMAL1 protein levels, confirming its role in regulating BMAL1 stability through K48-linked polyubiquitination and proteasomal degradation (Ullah et al., 2020)
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[DOI] [PubMed] [Google Scholar] Stacpoole PW, Gilbert LR, Neiberger RE, Carney PR, Valenstein E, Theriaque DW, Shuster JJ
