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Mol Biol (Mosk) 47:591601 Lo Cicero L, Madesis P, Tsaftaris A, Lo Piero AR (2015) Tobacco plants over-expressing the sweet orange tau glutathione transferases (CsGSTUs) acquire tolerance to the diphenyl ether herbicide fluorodifen and to salt and drought stresses

In renal tubular epithelial cells treated with calcium oxalate (CaOx) to induce kidney stone formation, CHAC1 expression increases alongside a decreased GSH level, reduced GPX4 activity, increased iron and MDA content and elevated ROS and lipid peroxidation

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FIGURE 2 Thiol-Dependent The most widespread and perhaps the best characterized pathway for formaldehyde detoxification employs reactive thiols as the initial formaldehyde acceptor