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doi:10.1177/2058738418775241
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Intramuscular B12 injections represent the standard treatment for deficiency due to malabsorption (such as pernicious anaemia) or when neurological symptoms are present
The neurovascular unit uncoupling initiates glial activation, neuronal apoptosis, blood-retinal barrier leakage, and ischemia, shifting the understanding of DR from a solely vascular disorder to a neurovascular one where early NVU impairment predicts functional deficits like reduced contrast sensitivity and progression to vision-threatening complications (34)
