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Appropriate supplementation can be very helpful for dogs that are Vitamin B12 deficient, particularly when they also have chronic gastrointestinal disease, exocrine pancreatic insufficiency (EPI) and/or other absorption disorders

The serum test measures all B12 present in the blood, as well as all substances that are chemically similar to vitamin B12

The circadian phase, response to light, and clock gene expression have been shown to differ between older and younger adults [43], which might cause a different response to VitB12

While vitamin B12 injections are generally considered safe, there are some contraindications to this form of treatment