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Description
Topical application provides immediate protective benefit during exposure, but the cumulative structural improvements in collagen and skin elasticity require weeks of consistent use before they become visible

J.GadgeelS.EstebanE.et al (2021)

General principles of compound absorption, distribution, metabolism and elimination as well as specific data from studies with Pycnogenol are summarized and discussed in this review

Endocrinol (2012) 153(8):372434
