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Agrobiol Rec 11:612 Ciesielska-Figlon K, Wojciechowicz K, Wardowska A, Lisowska KA (2023) The immunomodulatory effect of Nigella sativa

They bind to specific receptors on cell surfaces to trigger targeted biological responses

[0366] In another embodiment, a recombinant DNA vector is used to transfect a cell line that produces an antibody having a desired effector function, (e.g., a constant region of a human immunoglobulin) in which case, the replacement gene contained in the recombinant vector may encode all or a portion of a region of an ALPPL2/ALPP specific antibody and the target sequence contained in the recombinant vector allows for homologous recombination and targeted gene modification within the antibody producing cell

18.2.2 Treatment of de novo autoimmune hepatitis is like conventional autoimmune hepatitis