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Transactive response DNA-binding protein 43 kDa (TDP-43) is an RNA-binding protein that abnormally accumulates in the motor neurons of ALS patients [116]
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3.3.2 Fenton reactions and the bidirectional effects of iron homeostasis imbalance Free Fe + participates in the Fenton reaction, leading to the generation of hydroxyl radicals (OH), which represents a crucial step in initiating the lipid peroxidation chain reaction (96)
