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Most AAIs deliver a maximum of 300 g of epinephrine, although the recommended dose in teenagers and adults is 500 g, resulting in significant underdosing that may lead to deadly results (Marie 2020)

NMDA receptors in immune competent cells

Upon activation, Receptor Activator of Nuclear Factor-B Ligand (RANKL), is produced by CD4 + T cells, which attaches to the RANK receptor and triggers the NF-B and MAPK signaling pathways

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