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Description
Plast Reconstr Surg
These effects appear to persist beyond the active administration window, suggesting gene expression-level influence rather than simple receptor agonism
There was Nos1 (decreased expression), Nos2 (increased expression), Plcg1 (decreased expression), Prkcg (increased, and then decreased expression), Ptgs2 (increased expression), and no effect on Nos3 and Ptk2
Experiments often involve rodent or cell-based systems and measure metabolic flux, markers in adipose and muscle tissues, and transcription patterns affected by NNMT activity
