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FIGURE 5 3.5 Nitazoxanide reduced the mRNA expression of ER stress markers in rats with MTX-hepatotoxicity To determine whether the hepatoprotective effects of NTZ against MTX-hepatotoxicity are associated with ER stress reduction, mRNA expression and the protein level of ER stress markers were determined in liver homogenates

T3 mediates essential human physiological functions through thyroid nuclear receptor binding, regulating transcriptional processes governing metabolism, growth, and development (Su et al., 2021), while meta-analytical evidence indicates similar U-shaped correlations between FT3 and gestational hypertension/preeclampsia

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