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Description
Oxidative stress induces NFB activity and Urata et al showed blocking activation of NFB by anti-sense strategies prevented cytokines (TNF and IL-1)-induced increase in GCLC transcription in mouse endothelial cells (Urata et al., 1996)
Recent studies have shown that, in mammalian cells, most of the activesite disulphides in the ER oxidoreductases are reduced under normal steadystate conditions (Jessop & Bulleid, 2004)
[DOI] [PubMed] [Google Scholar] Capron A, Riveau G, Grzych JM, Boulanger D, Capron M and Pierce R
A stay of execution: ATF4 regulation and potential outcomes for the integrated stress response
