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Clear cell sarcoma of tendons and aponeuroses in pediatric patients: a report from the Italian and German Soft Tissue Sarcoma Cooperative Group

This Review aims to revisit the discovery and evolution of androgen receptor targeting therapeutics for the treatment of advanced-stage prostate cancer over the years and to discuss the upcoming future and challenges in the treatment of this common cancer

Moderate improvement in binding affinity at the hMC4R was observed, likely due to proximity effects and increasing the moles of pharmacophore present, but not indicative of cooperative or multivalent binding
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