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The abovementioned international group has now extended their study, using the 10 mg dosage, to assess long-term safety over ~4 years of extended repeated 3-month courses of UPA in 64 premenopausal women

Our results suggest that Plasmodium infection also creates a redox imbalance in its host cell (depicted by a drop in the host GSH: GSSG ratio) due to accumulation and efflux of redox active metabolites

Similarly, researchers have developed a platinum nanocluster (Pt@TAT/sPEG) with pH responsiveness and nuclear targeting properties to simultaneously target lactate dehydrogenase and exacerbate DNA damage, thereby promoting the death of TC cells [275]

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