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Likewise, meso-zeaxanthin exhibited no toxicity in rats even at doses of up to 200 mg/kg per day [87]

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The effects of age on the innate immune response include a decrease in pathogen recognition, chemotaxis, and phagocytosis, and in adaptive immunity, a decrease in the number of virgin T-lymphocytes and reduced cytotoxicity, as well as in the quality and quantity of antibodies [26]

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