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in colon tissue, assessing NO levels and oxidative stress (MDA levels) (as result of the lysis of endothelial cells) and ischemia/reperfusion injury, both as a spontaneous course [when blood supply was deprived via ligation (IC rats)] and a more exaggerated course [after ligation removal (IC + RL rats)] in immediate post-ligation time

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So, if for example you experience worse fatigue after B12 injections, it might be a brief phase where your body is still using the unhealthy red blood cells