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We elected to proceed with limb salvage surgery to achieve a functional rather than survival outcome, which seems more important in the setting of widespread metastasis and poor prognosis

Kallis PJ, Price A, Dosal JR, Nichols AJ, Keri J

35 Common doses are 5 to 15 mg of bisacodyl orally per day or 10 mg suppository rectally per day and 1 to 2 tablets of senna orally twice daily
