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Importantly, BPC-157 shows no direct angiogenic effect on endothelial cell cultures, suggesting its pro-angiogenic activity requires the context of injury and healing responses present in vivoa safety feature that may limit unwanted neovascularization in healthy tissues
The continued treatment with 1 M was done as this concentration is within range of the serum concentrations of the sum of tamoxifen and its metabolites in breast cancer patients treated with tamoxifen [24]
The authors concluded that intravenous BPC157 was welltolerated, but stressed that larger, longerterm trials are needed
Sadar et al
